目的:了解兰州市城区孕产妇叶酸知信行及相关卫生服务情况，为完善此项健康策略提供数据参考。方法:采用横断面研究方法，以年龄段分层......

Two new folate-derived analogues,named uncarophyllofolic acids A (1) and B (2),respectively,were isolated from the Uncar......

Hyperhomocysteinemia (Hhcy) is an independent risk factor for Alzheimer\'s disease (AD).Visual dysfunction is commonly......

...

Lipid-polymer hybrid nanoparticles (LPNPs) are polymeric nanoparticles enveloped by lipid layers that combine the highly......

Colon cancer refers to cancerous growth in colon,rectum or cecum [1].Oral anti-cancer drug has been advocated as adjuvan......

Gastric cancer is the second leading cause of cancer-related death worldwide.RNA nanotechnology has recently emerged as ......

Objective Dietary habits and lifestyle have been related to the risk of nasopharyngeal carcinoma(NPC),but information on......

Aim: Previous studies have reported inconsistent findings regarding the associations between homocysteine (Hcy), vitamin......

Cullin 3(CUL3)serves as a scaffold protein and assembles a large numberof ubiquitin ligase complexes.It is involvedin mu......

Background & Aims: Aberrant DNA methylation in gene promoter plays a major role in tumorigenesis.Previous studies have s......

Cisplatin is one of the most widely used agents in the treatment of a variety of tumors [1].However, its toxicity, cross......

Objective:To analyze the associations between early concentrations of Hcy, folate and VB12 and subsequent events of adve......

Background: Aberrant DNA methylation plays a significant role in tumorigenesis which can be induced by folate deficiency......

Retinal diseases are the primary causes for visual impairment.One of the greatest challenges for retinal diseases therap......

...

Chitosan was used as drug vector,folate as tumor targeting ligand to directly prepare Folate-decorated chitosan(FA-CTS) ......

...

Spatiotemporal control of singlet oxygen (1O2) release is a major challenge for photodynamic therapy (PDT) against cance......

　　Nowadays,the treatment efficacy of the chemotherapeutic drugs are far from satisfying on account of poor tumor speci......

　　Gastric cancer is second commonest cancer in China,and is the second leading cause of cancer-related death worldwide......

Objective:To prepare folate liposome complexes of recombinant plasmid pEGFP/SDF-1/KDEL wich contained intrakine SDF-1/KD......

Fluorescent probes play a key role in modern biomedical research. As compared to inorganic quantum dots (QDs) composed w......

In this study, an amphiphilic copolymer folate-succinyl-methionine-chitosan-octyl (FSMCO) was successfully synthesized s......

The detection of protein/small molecule interactions plays important roles in drug discovery and protein/metabolite inte......

Aim: To investigate the changes in plasma level of the chemokine RANTES (regulated upon activation, normal T cells expr......

Multifunctional nanocarriers with multilayer core-shell architecture were prepared by coating superparamagnetic Fe3O4 na......

Objective: To explore the relationship between genetic polymorphisms in methylenetetrahydrofolate reductase (MTHFR), met......

Serum proteins represent an important class of drug and imaging agent delivery vectors.In this minireview,key advantages......

Since synthetic vitamins were used to fortify food and as supplements in the late 1930 s, vitamin intake has significant......

AIM: To evaluate the association between the levels of homocysteine(Hcy), folate, vitamin B12 in human immunodeficiency ......

One-carbon unit transfer reaction of folate cofactor model compound, 1-acetyl-2-methyl-imidazolinium, with 1,2-diaminobe......

宫颈癌是影响女性生活健康最常见的生殖系统恶性肿瘤之一，其发生、发展与多种因素相关，除环境危险因素（如人乳头瘤病毒感染、多个性伴......

目的 探讨同型半胱氨酸(Hcy)与脑分水岭梗死(CWI)的关系.方法 58例CWI患者(观察组)和56例健康者(对照组),采用荧光偏振免疫分析法......

AIM:To investigate serum levels of homocysteine (Hcys) and the risk that altered levels carry for thrombosis development......

Colorectal cancer (CRC) is one of the most common malignancies and causes of cancer deaths throughout the world. Endosco......

Objective: To prepare folate liposome complexes of recombinant plasmid pEGFP/SDF-1/KDEL with contained intrakine SDF-1/K......

目的了解北京社区人群血浆叶酸水平,探究影响叶酸水平的相关因素。方法采用横断面研究设计,对北京石景山社区居民进行问卷调查及血......

Objective This study aimed to investigate the effects of N,N-dimethylglycine(DMG) on the concentration and metabolism of......

Objective To explore the effect of L-dopa on plasma homocysteine and folic acid in patients with Parkinsons’s disease (......

ＡｎａｌｙｓｉｓｏｆｔｈｅｃｈａｒａｃｔｅｒｉｓｔｉｃｓｏｆｆｏｌａｔｅｂｉｎｄｉｎｇｐｒｏｔｅｉｎｓａｎｄｉｔｓｒｅｌａｔｉｏｎｓｈｉｐｗｉｔｈｅｘｐｒｅｓｉｏｎｏｆｍｕｌｔｉｄｒｕｇｒｅｓｉｓｔａｎｃｅＰｇｌｙｃｏｐｒｏｔｅｉｎｉｎｍｙｅｌｏｄ... AnalysisofthecharacteristicsoffolatebindingproteinsanditsrelationshipwithexpresionofmultidrugresistancePglycoprot......

AIM: To determine whether Helicobacter pylori (H pylori) infection caused hyperhomocysteinemia by altering serum vitamin......

AIM: To investigate the effect of vitamin supplements on homocysteine levels in patients with celiac disease. METHODS: V......

...

Purpose:Accumulative evidence suggests that folate has a protective effect on gastric cancer. The methylenetetrahyd-rofo......

The relationship between hyperhomocysteinemia and coronary artery disease (CAD) was investigated and the influence of en......

目的观察叶酸受体α(folate receptor alpha,FOLR1)在胰腺癌中的表达水平,为叶酸受体α靶向性分子显像技术的建立提供依据。方法采......

AIM: To evaluate the effects of folic acid on epithelial apoptosis and expression of Bcl-2 and p53 in the tissues of pre......

AIM: To investigate the behaviour of total plasma homocysteine (tHcy) and its most common genetic determinant defect, th......

Objective To observe the effect of Pinggan Qianyang Recipe(PQR)on inhibiting angiotensinⅡ(AngⅡ)induced proliferation a......